产品货号：
Z10361
中文名称：
ACE抗体
英文名称：
Anti-ACE Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-ACE Antibody |
| 指标别名 | ACE;ACE1;Angiotensin converting enzyme;CD143;DCP;DCP1;Dipeptidyl carboxypeptidase I;Kininase II;MVCD3 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC,IF |
| 基因名称 | ACE |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human ACE recombinant protein (Position:K651-Y864).Human ACE shares 73% and 76% amino acid (aa) sequences identity with mouse and rat ACE,respectively. |
| 实际分子量 | 150～180KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Angiotensin-converting enzyme (ACE),an exopeptidase,is a circulating enzyme that participates in the body's renin-angiotensin system(RAS),which mediates extracellular volume (i.e.that of the blood plasma,lymph and interstitial fluid),and arterial vasoconstriction.It is secreted by pulmonary and renal endothelial cells and catalyzes the conversion of decapeptide angiotensin I to octapeptide angiotensin II.Using a DNA marker at the growth hormone gene locus,which they characterized as 'extremely polymorphic' and which showed no recombination with ACE,ACE was mapped to 17q22-q24,consistent with the in situ hybridization mapping to 17q23.ACE,or kininase II,is a dipeptidyl carboxypeptidase that plays an important role in blood pressure regulation and electrolyte balance by hydrolyzing angiotensin I into angiotensin II,a potent vasopressor,and aldosterone-stimulating peptide.The enzyme is also able to inactivate bradykinin,a potent vasodilator. |
| Uniprot ID | P12821 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | angiotensin I converting enzyme |
| 蛋白名全称 | Angiotensin-converting enzyme |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 Immunohistochemistry in frozen section (IHC-F) 1:50～400 Immunocytochemistry/Immunofluorescence(ICC/IF) 1:50～400 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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